Kaeberlein Lab Publications
2008
Managbanag, J. R., Witten, T. M., Bonchev, D., Fox, L. A., Tsuchiya, M., Kennedy, B.K. and Kaeberlein, M. (2008). Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity. 3, e3802. Download PDF
Kaeberlein, M. and Kennedy, B.K. (2008). Hot topics protein translation, 2008. Aging Cell 7, 777-782. Download PDF
Steinkraus, K. A., Kaeberlein, M. and Kennedy, B.K. (2008). Replicative aging in yeast: the means to the end. Ann Rev Cell Dev Biol 24, 29-54. Download PDF
Kaeberlein, M. (2008). A molecular age barrier. Nature 454, 709-710. Download PDF
Kaeberlein, M. (2008). The ongoing saga of sirtuins and aging. Cell Metab 8, 4-5. Download PDF
Smith, E.D., Kaeberlein, T.L., Lydum, B.T., Welton, K.L., Kennedy, B.K., Fox, L.A., and Kaeberlein, M. (2008). Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans. BMC Dev Biol 8, 49. Download PDF
Steffen, K.K., MacKay, V.L., Kerr, E.O., Tsuchiya, M., Hu, D., Fox, L.A., Dang, N., Johnston, E.D., Oakes, J.A., Tchao, B.N., Pak, D.N., Fields, S.F., Kennedy, B.K., and Kaeberlein, M. (2008). Yeast life span extension by depletion of 60S ribosomal subunits is mediated by Gcn4. Cell 133, 292-302. Download PDF
Effros, R.B., Austad, S., Blau, H., Chesselet, M.F., Ingram, D., Johnson, T.E., Kaeberlein, M., Lundblad, V., McCarter, R., McElhaney, J., and Saag, M. (2008). The biological sciences section program at the 60th annual meeting of the gerontological society of america. J. Gerontol. 63, 331-337. Download PDF
Smith, E.D., Tsuchiya, M., Fox, L.A., Dang, N., Hu, D., Kerr, E.O., Johnston, E.D., Tchao, B.N., Pak, D.N., Welton, K.L., et al. (2008). Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. Genome Research 18, 564-570. Download PDF
Steinkraus, K.A., Smith, E.D., Davis, C., Carr, D., Pendergrass, W.R., Sutphin, G.L., Kennedy, B.K., and Kaeberlein, M. (2008). Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in C. elegans. Aging Cell Mar 10; [Epub ahead of print]. Download PDF
Murakami, C.J., Burtner, C.R., Kennedy, B.K., Kaeberlein, M. (2008) A method for high-throughput quantitative analysis of yeast chronological life span. J. Gerontol. 63, 113-121. Download PDF
Sutphin, G.L., Kaeberlein M. (2008) Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes. Exp Gerontol. 43, 130-135. Download PDF
Schmidlin T., Kaeberlein M., Kudlow B. A., Mackay V., Lockshon D., Kennedy B. K. (2008) Single-gene deletions that restore mating competence to diploid yeast. FEMS Yeast Res. 8, 276-286. Download PDF
2007
Kaeberlein M., Kennedy, B. K. (2007) Protein translation, 2007 Aging Cell 6, 731-734. Download PDF
Kaeberlein M. (2007) Molecular basis of ageing. EMBO Rep 8, 907-911. Download PDF
Kaeberlein M., Kennedy, B. K. (2007). Does resveratrol activate yeast Sir2 in vivo. Aging Cell 6, 415-416. Download PDF
Kaeberlein M., Burtner, C. R., Kennedy, B. K. (2007). Recent developments in yeast aging. PLoS Genet 3, e84. Download PDF
Kaeberlein M., Powers, R. W. (2007). Sir2 and calorie restriction in yeast: A skeptical perspective. Age Res Rev 6, 128-140. Download PDF
Kennedy B. K., Steffen, K. K., Kaeberlein M. (2007). Ruminations on dietary restriction and aging. Cell Mol Life Sci 64, 1323-1328. Download PDF
Kaeberlein M. (2007). Longevity genomics across species. Current Genomics 8, 73-78. Download PDF
Lockshon, D., Surface, L. E., Kerr, E. O., Kaeberlein M., Kennedy B. K., (2007). The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function. Genetics 175, 77-91. Download PDF
Smith E. D., Kennedy B. K., Kaeberlein M. (2007). Genome-wide identification of conserved longevity genes in yeast and worms.. Mech Ageing Dev 128, 106-111. Download PDF
2006
Kaeberlein T. L. , Smith E. D., Tsuchiya M., Welton K. L., Thomas J. H., Fields S., Kennedy B. K., Kaeberlein M. (2006). Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell 5, 487-494. Download PDF
Tsuchiya, M, Dang, N., Kerr, E. O., Hu, D., Steffan, K. K., Oakes, J. A., Kennedy B. K., Kaeberlein M. (2006). Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.. Aging Cell 5, 505-514. Download PDF
Kaeberlein, M., Rabinovitch, P. S. (2006). Grapes versus gluttony. Nature 444, 280-281. Download PDF
Kaeberlein, M. (2006). Genome-wide approaches to understanding human aging. Human Genomics 2, 422-428. Download PDF.
Kaeberlein, M., Steffen, K. K., Hu, D., Dang, N., Kerr, E. O., Tsuchiya, M., Fields, S., and Kennedy, B. K. (2006). Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312, 1312; author reply 1312. Download PDF
Powers, R. W., 3rd, Kaeberlein, M., Caldwell, S. D., Kennedy, B. K., and Fields, S. (2006). Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev 20, 174-184. Download PDF
Kaeberlein, M., Hu, D., Kerr, E. O., Tsuchiya, M., Westman, E. A., Dang, N., Fields, S., and Kennedy, B. K. (2006). Author's Reply. PLoS Genet 2, e34. Download PDF
Kaeberlein, M. (2006). Application of high-throughput technologies to aging-related research. In Handbook of models for human aging, P. M. Conn, ed. (Boston, Elsevier Press), pp. 207-218.
Kaeberlein, M. (2006). Longevity and aging in the budding yeast. In Handbook of models for human aging, P. M. Conn, ed. (Boston, Elsevier Press), pp. 109-120.
2005
Kaeberlein, M., Hu, D., Kerr, E. O., Tsuchiya, M., Westman, E. A., Dang, N., Fields, S., and Kennedy, B. K. (2005). Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast. PLoS Genet 1, e69. Download PDF
Kennedy, B. K., Smith, E. D., and Kaeberlein, M. (2005). The enigmatic role of Sir2 in aging. Cell 123, 548-550. Download PDF
Kaeberlein, M., Powers, R. W., 3rd, Steffen, K. K., Westman, E. A., Hu, D., Dang, N., Kerr, E. O., Kirkland, K. T., Fields, S., and Kennedy, B. K. (2005). Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310, 1193-1196. Download PDF
Hudson, F. N., Kaeberlein, M., Linford, N., Pritchard, D., Beyer, R. P., and Rabinovitch, P. S., eds. (2005). Microarray analysis of gene expression changes in aging. In Handbook of the Biology of Aging, 6th edn (Academic Press).
Kaeberlein, M., and Kennedy, B. K. (2005). Large-scale identification in yeast of conserved ageing genes. Mech Ageing Dev 126, 17-21. Download PDF
Kaeberlein, M., Kirkland, K. T., Fields, S., and Kennedy, B. K. (2005). Genes determining yeast replicative life span in a long-lived genetic background. Mech Ageing Dev 126, 491-504. Download PDF
Kaeberlein, M., McDonagh, T., Heltweg, B., Hixon, J., Westman, E. A., Caldwell, S. D., Napper, A., Curtis, R., DiStefano, P. S., Fields, S., et al. (2005). Substrate-specific activation of sirtuins by resveratrol. J Biol Chem 280, 17038-17045. Download PDF
2004
Kaeberlein, M., Kirkland, K. T., Fields, S., and Kennedy, B. K. (2004). Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol 2, E296. Download PDF
Kaeberlein, M. (2004). Aging-related research in the "-omics" age. Sci Aging Knowledge Environ 2004, pe39. Download PDF